I'm on a ski trip right now. I packed my Transpack with my boots, helmet, gloves, neck gaitors, ski pants, and a complete set of layers for a day of skiing in case my luggage was delayed. My Transpack fits perfectly in the overhead bins of any decent sized airplane. Then I take a soft briefcase that I can wear across my body that holds my laptop, wallet, glasses, personal items, etc. Those two items are my carry ons.
In my checked luggage is my suitcase with a soft purse to use in the evenings in lieu of the briefcase, and I took my skis, poles, an extra pair of shoes, and two more clothing items in my SporTube. Since both the suitcase and SporTube wheel, and I have two free hands with the Transpack on my back and briefcase across my body, I can manage all four pieces of luggage fairly easily. I do look like a Sherpa though and it's tricky getting the Transpack back on my back in the airplane after landing, but it works for me!